Ashley Smith-Brown could make his league debut for Oldham in Saturday’s clash with Crewe.
The defender joined the Latics last Friday on a season-long loan from Plymouth but was not eligible for their league opener against Forest Green.
He did make his full debut in the Leasing.com Trophy win over Liverpool Under-21s on Wednesday, while David Wheater, Gary Woods, Zak Mills, Scott Wilson and Sonhy Sefil were the new signings who started the loss to Forest Green.
Summer recruit Desire Segbe Azankpo suffered an ankle injury during the win over Liverpool and could be set for a spell on the sidelines.
Defenders Olly Lancashire and Nicky Hunt could be in contention for Crewe.
The pair both picked up injuries during pre-season, with Lancashire suffering a groin problem and Hunt sidelined by a knee issue.
But both have stepped up their training in a bid to be available for Saturday’s clash.
If neither makes it then boss David Artell may again deploy midfielder Ryan Wintle at the back after praising his performance in their opening defeat by Plymouth.