Matt Mills will miss out for Forest Green when they welcome Leyton Orient to the New Lawn.
Head coach Mark Cooper has revealed the defender injured his back during training this week.
Also unavailable for selection are fellow defenders Joseph Mills, Farrend Rawson and Liam Shephard.
Rovers are without a win in eight matches in Sky Bet League Two.
Forward Louis Dennis could feature for Orient having made his long-awaited return from injury in midweek.
Summer signing Dennis featured for an hour playing for the reserves and grabbed a goal.
Goalkeeper Sam Sargeant and defenders Myles Judd and Joe Widdowson also claimed valuable minutes during that match and could be in contention for this weekend’s squad.
Orient have had a mixed bag of results in recent weeks, picking up two draws, two wins and two losses in their last six games.