Tottenham could be scrambling around to field a side for their Premier League curtain-closer against Everton.
Harry Winks (groin), Harry Kane (ankle), Jan Vertonghen (ankle) and Davinson Sanchez (thigh) are all definitely out, while Danny Rose (hamstring) and Victor Wanyama (thigh) are doubts.
Son Heung-min and Juan Foyth are also both suspended, though Vincent Janssen returns after he was ineligible in the Champions League.
Everton will be without forwards Richarlison and Dominic Calvert-Lewin.
Richarlison has been ruled out with the rib injury which has troubled him since the 4-0 win over Manchester United on April 21, while Calvert-Lewin suffered a knock in training.
Midfielder Andre Gomes is back from a three-match ban, but Seamus Coleman is doubtful with a groin problem.