Crawley must bounce back from a poor display against Swindon if they are to extend their Carabao Cup run with victory over Colchester.
Gabriele Cioffi will be keen to make changes after his side were thumped 4-0 at home by the Robins in Sky Bet League Two on Saturday.
Striker Ollie Palmer could step off the substitutes’ bench and into the starting line-up after recovering from a stress fracture.
Midfielder George Francomb and defender Joe McNerney are on the verge of returning from their respective injuries.
Colchester boss John McGreal will hope to name an unchanged side after his side’s 3-1 win over Newport.
Courtney Senior, Luke Norris, Brandon Comley and Ben Stevenson were all recalled for the come-from-behind win over County.
Callum Harriott and Luke Gambin are pushing to feature after coming off the bench on Saturday.
But Theo Robinson is once again ruled out through suspension after his recent sending-off against Crewe.